Latest findings encourage further investigation of the therapeutic potential of specific HMOs in food allergy
This study adds to accumulating evidence for direct, potentially beneficial, effects of HMOs in addition to their prebiotic role and demonstrates for the first time modulation of Ag–IgE complex activation of human epithelial cells that may have important implications for food-allergy. Furthermore, this study reinforces the concept that structurally different oligosaccharides have distinct biological activities. Thus in determining the composition of infant formula, careful selection of oligosaccharides with specific structures may allow for the provision of additional health benefits beyond any “bifidogenic” properties.
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